IRC SASL authentication primarily uses the same mechanisms as SASL in other protocols. Most commonly:

Client Support

Desktop Clients

Feature AdiIRC BitchX ChatZilla Colloquy HexChat IceChat Irssi Konversation KVIrc
Feature LimeChat mIRC Mozilla Thunderbird Quassel Textual WeeChat Srain Swirc Glirc

Web Clients

Feature IRCCloud Kiwi IRC The Lounge Mibbit PIRC.pl web client

Mobile Clients

Feature IRC for Android
AndroIRC
Colloquy
CoreIRC
IRCCloud
LimeChat
Palaver
Quasseldroid
YAAIC

Bouncers

Bots

Feature Limnoria Sopel (ex Willie) Moon Moon PyLink (clientbot) BitBot

Libraries

Feature cinch Ruby Communi C++ girc Go irc-framework JS Kitteh IRC Client Library Java Net::Async::IRC Perl pydle Python Rust irc Rust Warren Kotlin
Feature zIRC Python ChatSharp C#

Services Support

Feature Anope Atheme ChatServices